Now showing items 1-5 of 5
Quercetin-induced apoptosis involves increased hTERT enzyme activity of leukemic cells
(Taylor & Francis, 2011-09)
We aimed to examine the growth suppressive effects of quercetin on acute promyelocytic and lymphoblastic leukemia and chronic myeloid leukemia, and to find out whether the growth suppression is related to the blocking of ...
The importance of protein profiling in the diagnosis and treatment of hematologic malignancies
(Galenos Publishing House, 2011)
Proteins are important targets in cancer research because malignancy is associated with defects in cell protein machinery. Protein profiling is an emerging independent subspecialty of proteomics that is rapidly expanding ...
Bioactive Sphingolipids in response to chemotherapy: A scope on Leukemias
(Bentham Science Publishers, 2011-05)
Sphingolipids are major constituents of the cells with emerging roles in the regulation of cellular processes. Deregulation of sphingolipid metabolism is reflected as various pathophysiological conditions including metabolic ...
Therapeutic applications of bioactive sphingolipids in hematological malignancies
Sphingolipids are sphingosine-based lipid molecules that have important functions in cellular signal transduction and in a variety of cellular processes including proliferation, differentiation, programmed cell death ...
Role of autophagy in the progression and suppression of leukemias
Autophagy is a physiological process in which cellular components are degraded by the lysosomal machinery. Thereby, organelles are recycled and monomers are produced in order to maintain energy production. Current studies ...