Now showing items 1-8 of 8
BODIPY-conjugated chitosan nanoparticles as a fluorescent probe
(Taylor & Francis, 2017-10)
Recently, development of fluorescent nanoparticle-based probes for various bioimaging applications has attracted great attention. This work aims to develop a new type fluorescent nanoparticle conjugate and evaluate its ...
Reactions of acyl phosphonates with organoaluminum reagents: A new method for the synthesis of secondary and tertiary α-hydroxy phosphonates
The reactions of organoaluminum reagents (trimethylaluminum, triethylaluminum, etc.) with aryl and alkyl acyl phosphonates, which lead to the formation of α-hydroxy phosphonates in moderate to good yields, are reported. ...
A new proton sponge polymer synthesized by RAFT polymerization for intracellular delivery of biotherapeutics
(Royal Society of Chemistry, 2014-03)
A spermine-like polymer was synthesized via reversible addition- fragmentation chain transfer polymerization as a potential endosomal escaping agent. A new methacrylate monomer, 2-((tert-butoxycarbonyl)(2-((tert- ...
A ratiometric fluorescent probe for gold and mercury ions
A fluorescent probe that displays a ratiometric fluorescence response towards gold and mercury ions has been devised. Emitting at a relatively longer wavelength, the conjugated form of the fluorescent dye transforms in the ...
Electrophilic cyanate as a recognition motif for reactive sulfur species: Selective fluorescence detection of H2S
(American Chemical Society, 2016-01-05)
An ESIPT-based fluorescent dye, 3-hydroxyflavone, is chemically masked with an electrophilic cyanate motif in order to construct a fluorescent probe for cellular sulfur species. This novel probe structure, displays an ...
A fluorescein-based chemodosimeter for selective gold(III) ion monitoring in aqueous media and living systems
We constructed a turn-on type chemodosimeter based upon a fluorescein scaffold for the rapid, selective detection of gold(III) ions over other metal species. This novel probe structure offers distinct features including ...
A guanidinium modified rhodamine-based fluorescent probe for in vitro/vivo imaging of gold ions
(Royal Society of Chemistry, 2015-10-07)
We devised a rhodamine-based fluorescent probe functionalized with a guanidinium moiety, which both operates efficiently in pure aqueous media and displays a selective fluorescence response to Au3+ ions. We also demonstrated ...
A rhodamine/BODIPY-based fluorescent probe for the differential detection of Hg(ii) and Au(iii)
(Royal Society of Chemistry, 2014-02)
We described the design and synthesis of a molecular sensor based on a rhodamine/BODIPY platform that displayed differential fluorescence responses towards Hg2+ and Au3+ and demonstrated its utility in intracellular ion imaging.