Show simple item record

dc.contributor.advisorArtok, Leventen
dc.contributor.authorKuş, Melihen
dc.date.accessioned2014-07-22T13:50:49Z
dc.date.available2014-07-22T13:50:49Z
dc.date.issued2009en
dc.identifier.urihttp://hdl.handle.net/11147/3073
dc.descriptionThesis (Master)--İzmir Institute of Technology, Chemistry, İzmir, 2009en
dc.descriptionIncludes bibliographical references (leaves: 43-46)en
dc.descriptionText in English; Abstract: Turkish and Englishen
dc.descriptionx, 166 leavesen
dc.description.abstractα,β-Unsaturated ketones are important key reagents in organic synthesis. They are commonly synthesised through an aldol condensation reaction.Since Hayashi et al. reported the first Rh-catalyzed addition of aryl- and alkenylboronic acids to α,β-unsaturated ketones, the Rh-catalyzed addition of organoboron reagents to various unsaturated systems has become increasingly popular as a method of constructing C.C bonds. Organoboron reagents readily undergo transmetalation with Rh to form arylrhodium(I) species that are capable of inducing the nucleophilic arylation of various electrophilic sites (Sakai, et al. 1997, Hayashi and Yamasaki 2003). In this work, we have succesfully performed another example of the Rhcatalyzed reaction of arylboronic acids: a reaction of arylboronic acids with alkynes under a CO atmosphere to yield α,β-unsaturated ketones (Kuş, et al. 2008). As a consequence, the methodology established in this study proposes arelatively mild and simple way for the synthesis of α,β-unsaturated ketones.en
dc.language.isoengen
dc.publisherİzmir Institute of Technologyen
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject.lccQD305.K2 .K971 2009en
dc.subject.lcshKetonesen
dc.subject.lcshCarbonyl compoundsen
dc.subject.lcshOrganoboron compoundsen
dc.subject.lcshRhodium catalystsen
dc.subject.lcshAlkynesen
dc.titleSynthesis of α,β-unsaturated ketones by rhodium-catalyzed carbonylative arylation of internal alkynes with arylboronic acidsen
dc.typemasterThesisen
dc.contributor.authorIDTR114811
dc.contributor.departmentİzmir Institute of Technology. Chemistryen
dc.relation.publicationcategoryTezen_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record