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dc.contributor.authorGenc, Goezde
dc.contributor.authorBatigun, Ayseguel
dc.contributor.authorBayraktar, Oguz
dc.contributor.authorAltintas, Ozcan
dc.contributor.authorTunca, Umit
dc.contributor.authorHizal, Guerkan
dc.date.accessioned2021-02-12T18:52:30Z
dc.date.available2021-02-12T18:52:30Z
dc.date.issued2009
dc.identifier.isbn978-1-4244-3605-7
dc.identifier.urihttps://hdl.handle.net/11147/10679
dc.description14th National Biomedical Engineering Meetingen_US
dc.description/0000-0001-8767-6166; Hizal, Gurkan/0000-0003-1238-362X; Bayraktar, Oguz/0000-0003-4210-2825;en_US
dc.description.abstractAmphiphilic poly(methyl methacrylate)-b-poly(acrylic acid) (PMMA-b-PAA) copolymers with 4 and 6 arms were synthesized by Atomic Transfer Radical Polymerization (ATRP). The polymers were characterized by GPC, H-NMR and FTIR analysis. Polymer samples synthesized at various molecular weights between 18-80 kDa were investigated in terms of maximum loading capacity and critical micelle concentration by fluorescence spectroscopy. 4 arm PMMA-b-PAA (MW 30 kDa) was loaded with hydrophobic model drug indomethacin with an extremely high drug loading efficiency (22.5% drug content). Drug loaded polymer formed a stable and biodegradable complex in aqueous medium.en_US
dc.language.isoturen_US
dc.publisherIEEEen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleAcrylic Star Block Copolymers as Hydrophobic Drug Carriersen_US
dc.typeconferenceObjecten_US
dc.typeconferenceObjecten_US
dc.relation.journalBiyomut: 2009 14Th National Biomedical Engineering Meetingen_US
dc.contributor.departmentIzmir Isntitute of Technologyen_US
dc.identifier.startpage356en_US
dc.identifier.endpage+en_US
dc.identifier.wosWOS:000274345400091
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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