Browsing by Author "Georgieva, Elka R."

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Signature of an aggregation-prone conformation of tau

Eschmann, Neil A.; Georgieva, Elka R.; Ganguly, Pritam; Borbat, Peter P.; Rappaport, Maxime D.; Akdoğan, Yaşar; Freed, Jack H.; Shea, Joan-Emma; Han, Songi (Nature Publishing Group, 2017-03)

The self-assembly of the microtubule associated tau protein into fibrillar cell inclusions is linked to a number of devastating neurodegenerative disorders collectively known as tauopathies. The mechanism by which tau ...