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Categorization of species based on their microRNAs employing sequence motifs, information-theoretic sequence feature extraction, and k-mers
Background: Diseases like cancer can manifest themselves through changes in protein abundance, and microRNAs (miRNAs) play a key role in the modulation of protein quantity. MicroRNAs are used throughout all kingdoms and ...
Master regulators of posttranscriptional gene expression are subject to regulation
MicroRNAs (miRNAs) are small noncoding RNAs of 17-25 nt in length that control gene expression posttranscriptionally. As master regulators of posttranscriptional gene expression, miRNAs themselves are subject to tight ...
Systematic computational analysis of potential rnai regulation in toxoplasma gondii
RNA interference (RNAi) is the mechanism through which RNA interferes with the production of other RNAs in a sequence specific manner. Micro RNA (miRNA) is a type of RNA which is transcribed as pri-miRNAs and processed to ...
Comparison of four Ab initio MicroRNA prediction tools
MicroRNAs are small RNA sequences of 18-24 nucleotides in length, which serve as templates to drive post transcriptional gene silencing. The canonical microRNA pathway starts with transcription from DNA and is followed by ...
Progesterone/RANKL is a major regulatory axis in the human breast
(American Association for the Advancement of Science, 2013-04)
Estrogens and progesterones are major drivers of breast development but also promote carcinogenesis in this organ. Yet, their respective roles and the mechanisms underlying their action in the human breast are unclear. ...
Garlic accelerates red blood cell turnover and splenic erythropoietic gene expression in mice: Evidence for erythropoietin-independent erythropoiesis
(Public Library of Science, 2010)
Garlic (Allium sativum) has been valued in many cultures both for its health effects and as a culinary flavor enhancer. Garlic's chemical complexity is widely thought to be the source of its many health benefits, which ...