Browsing Molecular Biology and Genetics / Moleküler Biyoloji ve Genetik by IZTECH Author "Başsoy, Esen Yonca"

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Bioactive sphingolipids in docetaxel-induced apoptosis in human prostate cancer cells

Başsoy, Esen Yonca; Baran, Yusuf (Elsevier, 2012-03)

In this study, we examined the possible roles of ceramide/sphingosine-1-phosphate and ceramide/glucosyleceramide signaling in docetaxel-induced apoptosis by examining expression levels of the glucosyleceramide synthase and ...
Combination of fludarabine and imatinib induces apoptosis synergistically through loss of mitochondrial membrane potential and increases in caspase-3 enzyme activity in human K562 chronic myleloid leukemia cells

Baran, Yusuf; Öztekin, Coşkun; Başsoy, Esen Yonca (Informa Healthcare, 2010-06)

In this study, we aimed to show the synergistic apoptotic effects of imatinib/fludarabine combination in human K562 chronic myleloid leukemia (CML) cells. There was a significant increase in cytotoxicity of combination of ...