Browsing by Author "Zhivotovsky, B."

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5-Fluorouracil signaling through a calcium-calmodulin-dependent pathway is required for p53 activation and apoptosis in colon carcinoma cells

Can, G.; Akpınar, B.; Baran, Yusuf; Zhivotovsky, B.; Olsson, M. (Nature Publishing Group, 2013-09)

5-Fluorouracil (5-FU) is an anti-metabolite that is in clinical use for treatment of several cancers. In cells, it is converted into three distinct fluoro-based nucleotide analogs, which interfere with DNA synthesis and ...