Browsing by Author "Valade, David"

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Dicer-labile PEG conjugates for siRNA delivery

Kow, Siew Ching; Mccorroll, Joshua A.; Valade, David; Boyer, Cyrille; Dwarte, Tanya; Davis, Thomas P.; Kavallaris, Maria; Bulmuş, Volga (American Chemical Society, 2011-12-12)

Poly(ethylene glycol) (PEG) conjugates of Dicer-substrate small interfering RNA (DsiRNA) have been prepared to investigate a new siRNA release strategy. 3'-sense or 5'-antisense thiol-modified, blunt-ended DsiRNAs, inhibiting ...