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Browsing by Author "Boyer, Cyrille"
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Dicer-labile PEG conjugates for siRNA delivery
Kow, Siew Ching; Mccorroll, Joshua A.; Valade, David; Boyer, Cyrille; Dwarte, Tanya; Davis, Thomas P.; Kavallaris, Maria; Bulmuş, Volga (American Chemical Society, 2011-12-12)Poly(ethylene glycol) (PEG) conjugates of Dicer-substrate small interfering RNA (DsiRNA) have been prepared to investigate a new siRNA release strategy. 3'-sense or 5'-antisense thiol-modified, blunt-ended DsiRNAs, inhibiting ... -
Synthesis of heterotelechelic polymers with affinity to glutathione-S-transferase and biotin-tagged proteins by RAFT polymerization and thiol-ene reactions
Huang, Xin; Boyer, Cyrille; Davis, Thomas P.; Bulmuş, Volga (Royal Society of Chemistry, 2011-07)α-Glutathione (GSH), ω-biotin functionalized poly(N-isopropylacrylamide) (PNIPAAm) was synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization using a new R-group allyl functionalized ...