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Browsing by Author "Aypek, Hande"
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Alteration of protein localization and intracellular calcium content due to connexin26 D50A and A88V mutations
Aypek, Hande; Meşe, Gülistan (Türk Biyokimya Derneği, 2017-04)Introduction: Connexins (Cx) play essential roles in cellular homeostasis by forming gap junctions and non-junctional hemichannels. In vitro characterization of Cx26 mutations causing keratitis-ichthyosis-deafness (KID) ... -
Altered cellular localization and hemichannel activities of KID syndrome associated connexin26 I30N and D50Y mutations
Aypek, Hande; Bay, Veysel; Meşe, Gülistan (BioMed Central, 2016-02)Background: Gap junctions facilitate exchange of small molecules between adjacent cells, serving a crucial function for the maintenance of cellular homeostasis. Mutations in connexins, the basic unit of gap junctions, are ... -
CNT Incorporated Polyacrilonitrile/Polypyrrole Nanofibers as Keratinocytes Scaffold
Yardimci, Atike Ince; Aypek, Hande; Ozturk, Ozgur; Yilmaz, Selahattin; Ozcivici, Engin; Mese, Gulistan; Selamet, Yusuf (Trans Tech-Scitec Publications Ltd, 2019)Polypyrrole (PPy) is an attractive scaffold material for tissue engineering with its non-toxic and electrically conductive properties. There has not been enough information about PPy usage in skin tissue engineering. The ... -
Deciphering functions of aberrant hemichannels formed by connexin 26- I30N and D50Y mutations
Aypek, Hande (Izmir Institute of Technology, 2015-07)Cells need to communicate with each other for maintenance cellular and tissue homeostasis. Gap junctions are channel-forming structures that are formed by docking of two hemichannels on the plasma membrane of adjacent ...
