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Deep sequencing reveals two Jurkat subpopulations with distinct miRNA profiles during camptothecin-induced apoptosis

Erdoğan, İpek; Coşacak, Mehmet İlyas; Nalbant, Ayten; Akgül, Bünyamin (TUBITAK, 2018)

MicroRNAs (miRNAs) are small noncoding RNAs of about 19-25 nt that regulate gene expression posttranscriptionally under various cellular conditions, including apoptosis. The miRNAs involved in modulation of apoptotic events ...

A novel natural product, KL-21, inhibits proliferation and induces apoptosis in chronic lymphocytic leukemia cells

Adan Gökbulut, Aysun; Yaşar, Mustafa; Baran, Yusuf (Turkish Society of Hematology, 2015)

Objective: The aims of this study were to examine the cytotoxic and apoptotic effects of KL-21, a novel plant product (produced by naturin natural Products, İzmir, Turkey), on 232B4 chronic lymphocytic leukemia (CLL) cells ...