Browsing by Author "Doğan, Tunca"

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2-D thresholding of the connectivity map following the multiple sequence alignments of diverse datasets

Doğan, Tunca; Karaçalı, Bilge (ACTA Press, 2013)

Multiple sequence alignment (MSA) is a widely used method to uncover the relationships between the biomolecular sequences. One essential prerequisite to apply this procedure is to have a considerable amount of similarity ...
Automatic identification of evolutionary and sequence relationships in large scale protein data using computational and graph-theoretical analyses

Doğan, Tunca (İzmir Institute of Technology, 2012)

In this study, computational methods are developed for the automatic identification of functional/evolutionary relationships between biomolecular sequences in large and diverse datasets. Different approaches were considered ...
Automatic identification of highly conserved family regions and relationships in genome wide datasets including remote protein sequences

Doğan, Tunca; Karaçalı, Bilge (Public Library of Science, 2013-09)

Identifying shared sequence segments along amino acid sequences generally requires a collection of closely related proteins, most often curated manually from the sequence datasets to suit the purpose at hand. Currently ...