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Evidence for the presence of a second electron donor for the cytoplasmic thioredoxins in the yeast Saccharomyces cerevisiae
In yeast, the cytoplasmic thioredoxin system is composed of NADPH, thioredoxin reductase-1 (TRR1) and 2 thioredoxin genes (TRX1, TRX2). In this study, using yeast knockout mutants for TRR1, TRX1 and TRX2 genes, the role ...
Checkpoint deficient rad53-11 yeast cannot accumulate dNTPs in response to DNA damage
Deoxyribonucleotide pools are maintained at levels that support efficient and yet accurate DNA replication and repair. Rad53 is part of a protein kinase regulatory cascade that, conceptually, promotes dNTP accumulation in ...
Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast
(American Society for Microbiology, 2009-07)
Boron is a micronutrient in plants and animals, but its specific roles in cellular processes are not known. To understand boron transport and functions, we screened a yeast genomic DNA library for genes that confer resistance ...