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dc.contributor.authorUslu, Mehmet Emin
dc.contributor.authorErdoğan, İpek
dc.contributor.authorBayraktar, Oğuz
dc.contributor.authorAteş, Mehmet
dc.date.accessioned2017-04-10T11:15:04Z
dc.date.available2017-04-10T11:15:04Z
dc.date.issued2013
dc.identifier.citationUslu, M. E., Erdoğan, İ., Bayraktar, O., and Ateş, M. (2013). Optimization of extraction conditions for active components in equisetum arvense extract. Romanian Biotechnological Letters, 18(2), 8115-8131.en_US
dc.identifier.issn1224-5984
dc.identifier.urihttp://hdl.handle.net/11147/5274
dc.description.abstractResponse surface methodology was applied to predict optimum conditions for equisetum arvense extraction. Central composite design was used to monitor the effects of temperature, stirring speed, ethanol percent, extraction time, solid-liquid ratio on dependent variables such as, extract yield percent, total phenol content, total antioxidant capacity, silicic acid amount. According to the mathematical models obtained from the analysis, the highest values for yield percent, total phenol content, total antioxidant capacity and silicic acid amount were found to be 18.67 %, 123 mg gallic acid gr-1 dry weight extract, 1608 μM TEAC mg-1 dry weight extract and 0.0049 mg silicic acid mg-1 dry weight extract, respectively. The plant extracts were analyzed with HPLC to determine the phenolic content and compositional differences of extracts obtained at different extraction conditions. Plant extracts were also analyzed for their cytotoxic and antimicrobial activities. The high total antioxidant capacity and total phenolic content resulted in an increased cytotoxic effect on fibroblast cells. Equisetum arvense extracts showed antimicrobial activity against Staphylococcus epidermidis and Escherichia coli bacteria, however showed no effect against Candida albicans. © 2013 University of Bucharest.en_US
dc.language.isoengen_US
dc.publisherUniversity of Bucharesten_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimicrobial activityen_US
dc.subjectAntioxidanten_US
dc.subjectCytotoxicityen_US
dc.subjectEquisetum arvenseen_US
dc.subjectResponse surface methodologyen_US
dc.subjectSilicic aciden_US
dc.titleOptimization of extraction conditions for active components in equisetum arvense extracten_US
dc.typearticleen_US
dc.contributor.authorIDTR131394en_US
dc.contributor.iztechauthorUslu, Mehmet Emin
dc.contributor.iztechauthorErdoğan, İpek
dc.contributor.iztechauthorBayraktar, Oğuz
dc.relation.journalRomanian Biotechnological Lettersen_US
dc.contributor.departmentİYTE, Mühendislik Fakültesi, Kimya Mühendisliği Bölümüen_US
dc.identifier.volume18en_US
dc.identifier.issue2en_US
dc.identifier.startpage8115en_US
dc.identifier.endpage8131en_US
dc.identifier.wosWOS:000318221200007
dc.identifier.scopusSCOPUS:2-s2.0-84884178872


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