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dc.contributor.authorEkiz, Hüseyin Atakan
dc.contributor.authorCan, Geylani
dc.contributor.authorBaran, Yusuf
dc.date.accessioned2017-02-10T07:20:40Z
dc.date.available2017-02-10T07:20:40Z
dc.date.issued2012-03
dc.identifier.citationEkiz, H. A., Can, G., and Baran, Y. (2012). Role of autophagy in the progression and suppression of leukemias. Critical Reviews in Oncology/Hematology, 81(3), 275-285. doi:10.1016/j.critrevonc.2011.03.009en_US
dc.identifier.issn1040-8428
dc.identifier.urihttp://doi.org/10.1016/j.critrevonc.2011.03.009
dc.identifier.urihttp://hdl.handle.net/11147/4827
dc.description.abstractAutophagy is a physiological process in which cellular components are degraded by the lysosomal machinery. Thereby, organelles are recycled and monomers are produced in order to maintain energy production. Current studies indicate autophagy might suppress or augment survival of cancer cells. Therefore, by elucidating the role of autophagy in cancer pathogenesis, novel therapeutic intervention points may be revealed. Leukemia therapy has advanced in recent years; but a definitive cure is still lacking. Since autophagy often is deregulated in this particular type of cancer, it is clear that future findings will have clinical implications. This review will discuss the current knowledge of autophagy in blood cancers. © 2011 Elsevier Ireland Ltd.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.critrevonc.2011.03.009en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLeukemiaen_US
dc.subjectChemotherapeutic resistanceen_US
dc.subjectCell deathen_US
dc.subjectAutophagyen_US
dc.titleRole of autophagy in the progression and suppression of leukemiasen_US
dc.typereviewen_US
dc.contributor.authorIDTR119193en_US
dc.contributor.iztechauthorEkiz, Hüseyin Atakan
dc.contributor.iztechauthorCan, Geylani
dc.contributor.iztechauthorBaran, Yusuf
dc.relation.journalCritical Reviews in Oncology/Hematologyen_US
dc.contributor.departmentİYTE, Fen Fakültesi, Moleküler Biyoloji ve Genetik Bölümüen_US
dc.identifier.volume81en_US
dc.identifier.issue3en_US
dc.identifier.startpage275en_US
dc.identifier.endpage285en_US
dc.identifier.wosWOS:000301561200005
dc.identifier.scopusSCOPUS:2-s2.0-84856974622
dc.relation.publicationcategoryDiğeren_US


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