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dc.contributor.authorCeylan, Çağatay
dc.contributor.authorSevercan, Feride
dc.contributor.authorÖzkul, Aykut
dc.contributor.authorSevercan, Mete
dc.contributor.authorBozoğlu, Faruk
dc.contributor.authorTaheri, Nusret
dc.date.accessioned2017-02-09T07:29:51Z
dc.date.available2017-02-09T07:29:51Z
dc.date.issued2012-01
dc.identifier.citationCeylan, Ç., Severcan, F., Özkul, A., Severcan, M., Bozoğlu, F., and Taheri, N. (2012). Biophysical and microbiological study of high hydrostatic pressure inactivation of Bovine Viral Diarrheavirus type 1 on serum. Veterinary Microbiology, 154(3-4), 266-271. doi:10.1016/j.vetmic.2011.07.026en_US
dc.identifier.issn0378-1135
dc.identifier.urihttp://doi.org/10.1016/j.vetmic.2011.07.026
dc.identifier.urihttp://hdl.handle.net/11147/4815
dc.description.abstractThe effect of high hydrostatic pressure application on fetal bovine serum components and the model microorganism (Bovine Viral Diarrheavirus type 1 NADL strain) was studied at 132 and 220MPa pressure for 5min at 25°C. Protein secondary structures were found to be unaffected by an artificial neural network application on the amide I region for both untreated and HHP treated samples. FTIR spectroscopy study of both the HHP-treated and control samples revealed changes in the intensity of some bands in the finger-print region (1500-900cm -1) originating mainly from lipids which are thought to result from changes in the lipoprotein structure. The virus strain lost its infectivity completely after 220MPa HHP treatments. These results indicate that HHP can be successfully used for inactivation of pestiviruses while leaving structural and functional properties of serum and serum products unaffected. © 2011 Elsevier B.V.en_US
dc.language.isoengen_US
dc.publisherElsevieren_US
dc.relation.isversionof10.1016/j.vetmic.2011.07.026en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectArtificial neural networksen_US
dc.subjectFetal bovine serumen_US
dc.subjectFourier transform infrared spectroscopyen_US
dc.subjectHigh hydrostatic pressureen_US
dc.subjectVirusen_US
dc.titleBiophysical and microbiological study of high hydrostatic pressure inactivation of Bovine Viral Diarrheavirus type 1 on serumen_US
dc.typearticleen_US
dc.contributor.authorIDTR45775en_US
dc.contributor.iztechauthorCeylan, Çağatay
dc.relation.journalVeterinary Microbiologyen_US
dc.contributor.departmentİYTE, Mühendislik Fakültesi, Gıda Mühendisliği Bölümüen_US
dc.identifier.volume154en_US
dc.identifier.issue3-4en_US
dc.identifier.startpage266en_US
dc.identifier.endpage271en_US
dc.identifier.wosWOS:000299582000007
dc.identifier.scopusSCOPUS:2-s2.0-84855961633
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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