Now showing items 1-2 of 2
Effect of molecular architecture on cell interactions and stealth properties of PEG
(American Chemical Society, 2017-09)
PEGylation, covalent attachment of PEG to therapeutic biomolecules, in which suboptimal pharmacokinetic profiles limiting their therapeutic utility are of concern, is a widely applied technology. However, this technology ...
Effect of PEG grafting density and hydrodynamic volume on gold nanoparticle-cell interactions: an investigation on cell cycle, apoptosis, and DNA damage
(American Chemical Society, 2016-06-14)
In this study, interactions of polyethylene glycol (PEG)-coated gold nanoparticles (AuNPs) with cells were investigated with particular focus on the relationship between the PEG layer properties (conformation, grafting ...