Now showing items 1-10 of 28
Multidrug resistance in chronic myeloid leukemia
Chronic myeloid leukemia (CML) is characterized by the accumulation of Philadelphia chromosome-positive (Ph+) myeloid cells. Ph+ cells occur via a reciprocal translocation between the long arms of chromosomes 9 and 22 ...
Novel agents targeting bioactive sphingolipids for the treatment of cancer
(Bentham Science Publishers, 2013-01)
Sphingolipids are a class of lipids that have important functions in a variety of cellular processes such as, differentiation, proliferation, senescence, apoptosis and chemotherapeutic resistance. The most widely studied ...
Therapeutic potential of targeting ceramide/glucosylceramide pathway in cancer
Sphingolipids including ceramides and its derivatives such as ceramide-1-phosphate, glucosylceramide (GlcCer), and sphingosine-1-phosphate are essential structural components of cell membranes. They now recognized as novel ...
T cells in tumor microenvironment
Tumors progress in a specific area, which supports its development, spreading or shrinking in time with the presence of different factors that effect the fate of the cancer cells. This specialized site is called “tumor ...
Challenges in the preparation of optical polymer composites with nanosized pigment particles: A review on recent efforts
(Wiley-VCH Verlag, 2012-09)
Blends of nanosized pigment particles and polymers are widely believed to offer the potential for the design of novel or at least improved materials. This review critically evaluates the recent literature with regard to ...
Bioactive Sphingolipids in response to chemotherapy: A scope on Leukemias
(Bentham Science Publishers, 2011-05)
Sphingolipids are major constituents of the cells with emerging roles in the regulation of cellular processes. Deregulation of sphingolipid metabolism is reflected as various pathophysiological conditions including metabolic ...
On the application of the Exp-function method to nonlinear differential-difference equations
When applying the Exp-function method to nonlinear-differential difference equations, Bekir (2010)  reported incorrect results. © 2012 Elsevier Inc. All rights reserved.
The importance of protein profiling in the diagnosis and treatment of hematologic malignancies
(Galenos Publishing House, 2011)
Proteins are important targets in cancer research because malignancy is associated with defects in cell protein machinery. Protein profiling is an emerging independent subspecialty of proteomics that is rapidly expanding ...
Pathological hemichannels associated with human Cx26 mutations causing Keratitis-Ichthyosis-Deafness syndrome
Abstract Connexin (Cx) proteins form intercellular gap junction channels by first assembling into single membrane hemichannels that then dock to connect the cytoplasm of two adjacent cells. Gap junctions are highly specialized ...
Full bulk spin polarization and intrinsic tunnel barriers at the surface of layered manganites
(Nature Publishing Group, 2005-01)
The affect of full bulk spin polarization and intrinsic tunnel barriers on the surface of layered manganites were studied using a combination of surface-sensitive x-ray and tunnelling process. The surface bilayer of ...