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Recovery of phytochemicals (having antimicrobial and antioxidant characteristics) from local plants

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DoctoralThesis (4.592Mb)
Date
2010
Author
Altıok, Evren
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Abstract
The objective of the present work was to assess the selective isolation of polyphenols from olive leaf and grape skin, which are supplied from the main local plants. The effects of extraction conditions on the types and amounts of polyphenolic compounds and selective separation of them by adsorption were investigated. The batch adsorption and dynamic column studies were performed by silk fibroin and clinoptilolite. Kinetic models were used to determine the mechanism of adsorption. Dynamic column models were applied to optimize the operating parameters. The biological activities of isolated fractions from the crude extracts were determined by analyzing their antioxidant, antimicrobial and cytotoxic activities. Recovered trans-resveratrol significantly inhibited all pathogenic microorganisms. However, higher concentration of grape skin crude extract is required to achieve same inhibition. Although grape skin extract did not have any effect on prostate and breast cancer cells, trans-resveratrol has very significant inhibition effect.
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http://hdl.handle.net/11147/2881
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  • Phd Degree / Doktora





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DSpace@IZTECH is member of:

IZTECH Library, Gülbahçe Kampüsü - 35430 - Urla, İzmir / TURKEY
If you find any errors in content, please contact openaccess@iyte.edu.tr or library@iyte.edu.tr.

Creative Commons Lisansı
DSpace@IZTECH by IYTE Institutional repository is licensed under a Creative Commons Attribution-Gayriticari-NoDerivs 3.0 Unported License.


DSpace software copyright © 2002-2015  DuraSpace
Contact Us | Send Feedback
Theme by 
@mire NV