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dc.contributor.authorUluışık, İrem
dc.contributor.authorKaya, Alaattin
dc.contributor.authorÜnlü, Ercan Selçuk
dc.contributor.authorAvşar, Kadir
dc.contributor.authorKarakaya, Hüseyin Çağlar
dc.contributor.authorYalçın, Talat
dc.contributor.authorKoç, Ahmet
dc.date.accessioned2017-01-18T12:13:58Z
dc.date.available2017-01-18T12:13:58Z
dc.date.issued2011-02
dc.identifier.citationUluışık, İ., Kaya, A., Ünlü, E. S., Avşar, K., Karakaya, H. C., Yalçın, T., and Koç, A. (2011). Genome-wide identification of genes that play a role in boron stress response in yeast. Genomics, 97 (2),106-111. doi:10.1016/j.ygeno.2010.10.006en_US
dc.identifier.issn0888-7543
dc.identifier.urihttp://doi.org/10.1016/j.ygeno.2010.10.006
dc.identifier.urihttp://hdl.handle.net/11147/2810
dc.description.abstractBoron is an essential micronutrient for plants and it is either necessary or beneficial for animals. Studies identified only few genes related to boron metabolism thus far and details of how boron is imported into cells and used in cell metabolism are largely unknown. In order to identify genes that play roles in boron metabolism, we screened the entire set of yeast haploid deletion mutants and identified 6 mutants that were resistant to toxic levels of boron, and 21 mutants that were highly sensitive to boron treatment. Furthermore, we performed a proteomic approach to identify additional proteins that are significantly up-regulated by boron treatment. Our results revealed many genes and pathways related to boron stress response and suggest a possible link between boron toxicity and translational control.en_US
dc.description.sponsorshipThe Scientific and Technical Research Council of Turkey (TUBITAK) grant no. 104T213 Turkish Academy of Science GEBIP grant (to AK) The Biological Mass Spectrometer Grant from State Planning Organisation (DPT)en_US
dc.language.isoengen_US
dc.publisherElsevier BV.en_US
dc.relation.isversionof10.1016/j.ygeno.2010.10.006en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBoronen_US
dc.subjectBoric aciden_US
dc.subjectYeasten_US
dc.subjectGenomicsen_US
dc.subjectProteomicsen_US
dc.titleGenome-wide identification of genes that play a role in boron stress response in yeasten_US
dc.typearticleen_US
dc.contributor.authorIDTR21863en_US
dc.contributor.authorIDTR24898
dc.contributor.authorIDTR130617
dc.contributor.authorIDTR110769
dc.contributor.iztechauthorUluışık, İrem
dc.contributor.iztechauthorKaya, Alaattin
dc.contributor.iztechauthorÜnlü, Ercan Selçuk
dc.contributor.iztechauthorAvşar, Kadir
dc.contributor.iztechauthorKarakaya, Hüseyin Çağlar
dc.contributor.iztechauthorYalçın, Talat
dc.contributor.iztechauthorKoç, Ahmet
dc.relation.journalGenomicsen_US
dc.contributor.departmentİYTE, Fen Fakültesi, Moleküler Biyoloji ve Genetik Bölümüen_US
dc.identifier.volume97en_US
dc.identifier.issue2en_US
dc.identifier.startpage106en_US
dc.identifier.endpage111en_US
dc.identifier.wosWOS:000287289100006
dc.identifier.scopusSCOPUS:2-s2.0-79451471883
dc.relation.tubitakinfo:eu-repo/grantAgreement/TUBITAK/SOBAG/104T213
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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