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dc.contributor.authorCeylan, Çağatay
dc.contributor.authorSevercan, Mete
dc.contributor.authorBozoğlu, Faruk
dc.contributor.authorSevercan, Feride
dc.date.accessioned2016-11-28T13:31:37Z
dc.date.available2016-11-28T13:31:37Z
dc.date.issued2009-06
dc.identifier.citationCeylan, Ç., Severcan, M., Bozoğlu, F., and Severcan, F. (2009). Evaluation of high hydrostatic pressure effects on bovine red blood cells and platelets. High Pressure Research, 29(2), 358-368. doi:10.1080/08957950902941014en_US
dc.identifier.issn0895-7959
dc.identifier.urihttp://dx.doi.org/10.1080/08957950902941014
dc.identifier.urihttp://hdl.handle.net/11147/2542
dc.description.abstractThe objective of this study was to investigate the effects of high hydrostatic pressure (HHP) on the stability of red blood cells (RBCs) and platelets. Bovine blood cells (n=5) were treated with the pressure of 55, 110, 154 and 220MPa at 25°C for 5min. Light microscopy, atomic force microscopy and flow cytometry studies revealed that RBCs were morphologically stable up until the 220MPa pressure treatments, at which surface modifications were observed. The platelets were found to be less stable than RBCs. HHP application did not cause any significant change in the signal intensity, band area and frequency values of the infrared bands with the exception that a significant variation was observed in the area of the cholesterol band. No statistically significant variations were observed in the secondary structure elements due to HHP treatment according to the artificial neural network study based on the FTIR data.en_US
dc.description.sponsorshipMiddle East Technical University Grant No: BAP-2004-07-02-00-48en_US
dc.language.isoengen_US
dc.publisherTaylor & Francisen_US
dc.relation.isversionof10.1080/08957950902941014en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBlooden_US
dc.subjectFlow cytometry (FC)en_US
dc.subjectHigh hydrostatic pressure (HHP)en_US
dc.subjectAtomic force microscopyen_US
dc.subjectFTIRen_US
dc.subjectFourier transform infrared spectroscopyen_US
dc.titleEvaluation of high hydrostatic pressure effects on bovine red blood cells and plateletsen_US
dc.typearticleen_US
dc.contributor.authorIDTR45775en_US
dc.contributor.iztechauthorCeylan, Çağatay
dc.relation.journalHigh Pressure Researchen_US
dc.contributor.departmentİYTE, Mühendislik Fakültesi, Gıda Mühendisliği Bölümüen_US
dc.identifier.volume29en_US
dc.identifier.issue2en_US
dc.identifier.startpage358en_US
dc.identifier.endpage368en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US


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